Home Bratislava Medical Journal 2016 Bratislava Medical Journal Vol.117, No.9, p.495-500, 2016

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Published Monthly, in English
Founded: 1919
ISSN 0006-9248
(E)ISSN 1336-0345

Impact factor 1.564


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Bratislava Medical Journal Vol.117, No.9, p.495-500, 2016

Title: 24-hour outpatient ECG as a screening method in patients with primary hyperparathyroidism
Author: A. Dokupilova, J. Payer


PURPOSE: Patients with primary hyperparathyroidism are characterized by increased calcium plasma concentrations, which in turn could have a potential to induce ECG changes, especially shortening of the QT interval. Therefore, the aim of this study was to evaluate, whether the routine 24-hours outpatient ECG monitoring could be used for screening the primary hyperparathyroidism.
METHODS: Totally, 31 patients (mean age, 59.2 ± 12.99 years) with primary hyperparathyroidism were compared to 20 healthy controls. All patients underwent mineral metabolism biochemical evaluation, ultrasound or scintigraphy of the neck, and a 24-hour outpatient ECG. The device detected QT, QTc, and RR intervals during a 24-hour period.
RESULTS: Significantly higher calcium concentrations were confirmed in patients when compared to controls (2.38 ± 0.12 vs 2.92 ± 0.29 mmol/l; p < 0.001).

However, no significant differences were found between controls and patients in QT interval and overall heart rate.
CONCLUSION: Although shortening of the QT interval is a common ECG finding in patients with hyperparathyroidism, it seems that 24-hour outpatient ECG is not suitable for primary hyperparathyroidism screening (Tab. 2, Fig. 4, Ref. 28).

Keywords: primary hyperparathyroidism, hypercalcemia, 24 hour outpatient electrocardiography, QT interval and QTc interval
Published online: 21-Sep-2016
Year: 2016, Volume: 117, Issue: 9 Page From: 495, Page To: 500

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