Home Bratislava Medical Journal 2016 Bratislava Medical Journal Vol.117, No.10, p.587-594, 2016

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Published Monthly, in English
Founded: 1919
ISSN 0006-9248
(E)ISSN 1336-0345

Impact factor 1.564


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Bratislava Medical Journal Vol.117, No.10, p.587-594, 2016

Title: Can N-terminal pro B-type natriuretic peptide, neutrophil-to-lymphocyte ratio, C-reactive protein help to predict short and long term mortality?
Author: I. Ozmen, Z. Karakurt, C. Salturk, F. Kargin, H. B. Takir, E. Aksoy, R. Sari, E. Celik, E. A. Tuncay, E. Yildirim, O. Y. Mocin, N. Adiguzel, S. Oztas, S. Gungor, G. Gungor


BACKGROUND: There is limited data about ICU, short and long-term mortality prediction of severe CAP with neutrophil-to-lymphocyte ratio (NLR): N-terminal proB- type natriuretic peptide (NT-proBNP): C-reactive protein (CRP).
AIM: Besides the known severity indexes of ICU, can NLR, NT-proBNP, CRP predict ICU, short and long term mortality?
METHODS: A retrospective cohort study was carried out in a level III ICU of a tertiary training hospital for chest diseases and thoracic surgery.
RESULTS: Over the study period, a total of 143 patients were enrolled in the study. The APACHE II scoring showed a significantly higher predicting performance for ICU mortality (p = 0.002). The performance for predicting short term mortality NLR (p = 0.039) and long term mortality NTproBNP (p = 0.002) had a significantly higher performance. The survival analysis revealed that mortality was significantly higher in patients with CURB65 score ≥ 4 (p = 0.047).

CONCLUSION: NLR, NTproBNP > 2000pg/mL can be used to predict pneumonia severity in ICU alike CURB65 and PSI. Higher NLR, APACHE II and atrial fibrillation can cause an important mortality factor in long term. Consequently, clinicians should take an attention for good cardiac evaluation and cardiac follow-up of patients with CAP (Tab. 4, Fig. 3, Ref. 36).

Keywords: atrial fibrillation, C-reactive protein, intensive care unit, pneumonia severity, neutrophil lymphocyte ratio, NT-proBNP, respiratory failure
Published online: 07-Nov-2016
Year: 2016, Volume: 117, Issue: 10 Page From: 587, Page To: 594

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