Home Bratislava Medical Journal 2016 Bratislava Medical Journal Vol.117, No.11, p.677-680, 2016

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Published Monthly, in English
Founded: 1919
ISSN 0006-9248
(E)ISSN 1336-0345
 

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Bratislava Medical Journal Vol.117, No.11, p.677-680, 2016

Title: The effect of mad honey on testosterone levels of male rats
Author: O. Tatli, Y. Karaca, S. Turkmen, G. S. Gulgen, A. Sahin, U. Eryigit, O. Fazli, E. Karaguzel, A. Mentese, A. Orem, A. Cansu, S. Turedi, A. Gunduz

Abstract: OBJECTIVE: We aimed to investigate the effect of mad honey on sexual performance.
BACKGROUND: In traditional medicine in Turkey, mad honey is used to improve appetite, to heighten mental alertness, to reduce joint pain, to eliminate gastrointestinal system pains and to increase sexual performance.
METHODS: In this experimental animal study eighteen Sprague Dawley male rats were randomized into three groups, a control group, a normal honey group and a mad honey group. Rats in the treatment groups were given a daily dose of 80 mg/kg normal honey or mad honey throughout the 30-day study period. Total testosterone, free testosterone, FSH, LH, estradiol, and progesterone levels were subsequently investigated from blood sera on day 30.
RESULTS: Comparison of blood total testosterone levels among the groups revealed significantly higher levels in the mad honey group compared to the normal honey and control groups (p = 0.006, p = 0.00). Free testosterone levels were also significantly higher in the mad honey group than in the normal honey and control groups (p = 0.023, p = 0.01). No statistically significant differences were determined for other hormonal measurements.
CONCLUSIONS: This study revealed a significant increase in both total and free testosterone levels in mad-honey group (Tab. 1, Fig. 2, Ref. 16).

Keywords: mad honey, grayanotoxin, traditional medicine, sexual performance, testosterone
Published online: 22-Nov-2016
Year: 2016, Volume: 117, Issue: 11 Page From: 677, Page To: 680
doi:10.4149/BLL_2016_130


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