Home Bratislava Medical Journal 2017 Bratislava Medical Journal Vol.118, No.5, p.255-257, 2017

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Published Monthly, in English
Founded: 1919
ISSN 0006-9248
(E)ISSN 1336-0345

Impact factor 1.564


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Bratislava Medical Journal Vol.118, No.5, p.255-257, 2017

Title: Measurement of intact parathormone during operation for primary hyperparathyroidism
Author: P. Libansky, S. Adamek, P. Broulik, M. Fialova, J. Kubinyi, J. Sedy, P. Pafko, D. Yershov, R. Lischke

Abstract: In this prospective study, the role of the intact parathormone (iPHT) levels for the verification of pathologic parathyroid tissue removal during parathyroidectomy, was analyzed in 441 patients diagnosed with primary hyperparathyroidism. The level of intact parathormone was obtained before the initial incision (baseline level) and 10 minutes after the pathologic parathyroid gland removal (control value). In 80 % of cases, the decrease of intact parathormone was more than 50 % of the baseline level. The comparison of preoperative and postoperative intact parathormone levels can also be used as marker of parathyroid hyperplasia or persistent hyperparathyroidism. This method is necessary mainly for performance of focused, miniinvasive approaches as well as in reoperations. This method is of significant benefit in cases of negative preoperative examination methods. The determination of intact parathormone level increases the success of parathyroidectomy (Ref. 26).

Keywords: primary hyperparathyroidism, intact parathormone, parathyroidectomy, surgery, human
Published online: 15-May-2017
Year: 2017, Volume: 118, Issue: 5 Page From: 255, Page To: 257

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