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Bratislava Medical Journal Vol.118, No.5, p.269-272, 2017 |
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Title: Anti-oxidative effect of resveratrol on aluminum induced toxicity in rat cerebral tissue | ||
Author: M. M. H. Zakaria, B. Hajipour, R. Estakhri, B. M. Saleh | ||
Abstract: INTRODUCTION: The direct protective effects of resveratrol against oxidative stress have been demonstrated in neuroglial cells, the mechanisms of these effects are not fully understood. The aim of this research was to study the effect of resveratrol on AL induced cerebral injury in rat. CONCLUSIONS: This study suggests that resveratrol is effective in preventing AL induced toxicity by reducing MDA production in cerebral tissue. Resveratrol also attenuated SOD and GPx suppression in cerebral tissue significantly. Our findings provide the rationale for further studies directed to understanding the mechanism of resveratrol in preventing neurodeterioration (Tab. 1, Ref. 35). |
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Keywords: aluminum, brain, resveratrol | ||
Published online: 15-May-2017 | ||
Year: 2017, Volume: 118, Issue: 5 | Page From: 269, Page To: 272 | |
doi:10.4149/BLL_2017_053 |
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