Home HOME Acta Virologica 2017 Acta Virologica Vol.61, No.3, p.280-288, 2017

Journal info


Quarterly,
Founded: 1957
ISSN 0001-723X
E-ISSN 1336-2305

Published in English

Aims and Scope
Editorial Info

Abstracted and Indexed
Submission Guidelines

Select Journal







Webshop Cart

Your Cart is currently empty.

Info: Your browser does not accept cookies. To put products into your cart and purchase them you need to enable cookies.

Acta Virologica Vol.61, No.3, p.280-288, 2017

Title: Large protein as a potential target for use in rabies diagnostics
Author: I. S. SANTOS KATZ, M. H. DIAS, I. F. LIMA, L. B. CHAVES, O. G. RIBEIRO, K. C. SCHEFFER, L. K. IWAI

Abstract: Rabies is a zoonotic viral disease that remains a serious threat to public health worldwide. The rabies lyssavirus (RABV) genome encodes five structural proteins, multifunctional and significant for pathogenicity. The large protein (L) presents well-conserved genomic regions, which may be a good alternative to generate informative datasets for development of new methods for rabies diagnosis. This paper describes the development of a technique for the identification of L protein in several RABV strains from different hosts, demonstrating that MS-based proteomics is a potential method for antigen identification and a good alternative for rabies diagnosis.

Keywords: rabies virus; large protein; street virus; target; mass spectrometry; proteomics
Published online: 28-Aug-2017
Year: 2017, Volume: 61, Issue: 3 Page From: 280, Page To: 288
doi:10.4149/av_2017_306


download file



© AEPress s.r.o
Copyright notice: For any permission to reproduce, archive or otherwise use the documents in the ELiS, please contact AEP.