Home Acta Virologica 2017 Acta Virologica Vol.61, No.3, p.353-360, 2017

Journal info


Quarterly, 72-88 pp. per issue
Founded: 1957
ISSN 0001-723X
E-ISSN 1336-2305

Published in English

Aims and Scope
Editorial Info

Abstracted and Indexed
Submission Guidelines

Select Journal







Webshop Cart

Your Cart is currently empty.

Info: Your browser does not accept cookies. To put products into your cart and purchase them you need to enable cookies.

Acta Virologica Vol.61, No.3, p.353-360, 2017

Title: Meet interesting abbreviations in clinical mass spectrometry: from compound classification by REIMS to multimodal and mass spectrometry imaging (MSI)
Author: D. LUPTÁKOVÁ, T. PLUHÁČEK, A. PALYZOVÁ, J. PŘICHYSTAL, J. BALOG, K. LEMR, I. JURÁNEK, V. HAVLÍČEK

Abstract: This feature article discusses two modern mass spectrometry abbreviations in their clinical applications. Rapid evaporative ionization mass spectrometry (REIMS) is reported as a molecular classification tool useful for spectral features definition prior to mass spectrometry imaging (MSI). REIMS is appreciated not only as an ionization technique coupled with a surgical device but particularly as a biomarker discovery tool. For more complex understanding of pathological processes at cellular and molecular levels, the importance of multimodal approach in imaging applications is documented in the context of fiducial markers needed for hyperspectral data fusion collected by optical microscopy, elemental and molecular MSI. Finally, pathogen inactivation needed prior to the sectioning of the infected tissue is reported, and the impact of formaldehyde crosslinking to signal reduction is discussed.

Keywords: REIMS; multimodal; mass spectrometry imaging; fiducial markers; pathogen inactivation
Published online: 28-Aug-2017
Year: 2017, Volume: 61, Issue: 3 Page From: 353, Page To: 360
doi:10.4149/av_2017_316


download file



© AEPress s.r.o
Copyright notice: For any permission to reproduce, archive or otherwise use the documents in the ELiS, please contact AEP.