Journal info
|
||
Select Journal
Journals
Bratislava Medical Journal Endocrine Regulations General Physiology and Biophysics Neoplasma Acta Virologica Current articles 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 Studia Psychologica Cardiology Letters Psychológia a patopsych. dieťaťa Kovove Materialy-Metallic Materials Slovenská hudbaWebshop Cart
Your Cart is currently empty.
Info: Your browser does not accept cookies. To put products into your cart and purchase them you need to enable cookies.
Acta Virologica Vol.61, No.3, p.372-376, 2017 |
||
Title: Two mice models for transferability of zoonotic bacteria via tick vector | ||
Author: B. SALLAY, T. VACULOVÁ, M. DERDÁKOVÁ, V. RUSŇÁKOVÁ TARAGEĽOVÁ, E. ŠPITALSKÁ, Ľ. ŠKULTÉTY | ||
Abstract: Spotted fever and typhus-related diseases caused by rickettsiae, Lyme borreliosis induced by spirochetes from Borrelia burgdorferii sensu lato complex, and Q fever evoked by Coxiella burnetii, are important zoonoses occurring worldwide. In order to study the pathogenesis of these infections, the efficacy of vaccines from the perspective of protection against the pathogens, pathogen – pathogen interactions during co-infections or pathogen-vector-host interrelationship, a suitable animal model should be established. In this study, we evaluated two mouse models – the C3H/N and Balb/c strains for susceptibility to infection and ability to transmit the pathogens via tick vector and to reveal the potential interactions between various bacterial tick-borne agents. Our results indicated that the C3H/N and Balb/c mice are well-accepted models of B. afzelii infection. However, they are not suitable for interaction studies with R. helvetica since the animals did not acquire rickettsiemia and do not transmit Rickettsia sp. to feeding ticks. |
||
Keywords: animal model; pathogen transferability; tick vector; Ixodes ricinus; Coxiella burnetii; Rickettsia helvetica; Borrelia afzelii | ||
Published online: 28-Aug-2017 | ||
Year: 2017, Volume: 61, Issue: 3 | Page From: 372, Page To: 376 | |
doi:10.4149/av_2017_319 |
||
|
download file |
|