Home Bratislava Medical Journal 2017 Bratislava Medical Journal Vol.118, No.8, p.491-494, 2017

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Published Monthly, in English
Founded: 1919
ISSN 0006-9248
(E)ISSN 1336-0345
 

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Bratislava Medical Journal Vol.118, No.8, p.491-494, 2017

Title: Association between neutrophil/lymphocyte ratio with ductus arteriosus patency in preterm newborns
Author: M. T. Temel, M. E. Coskun, S. Akbayram, A. T. Demiryürek

Abstract: OBJECTIVE: The aim of this study was to assess the influence of neutrophil to lymphocyte (N/L) ratio and platelet indices on patent ductus arteriosus (PDA) in preterm infants.
BACKGROUND: PDA is a common problem with potentially serious associated morbidities in preterm neonates.
METHODS: Premature infants with hemodynamically significant PDA (n = 47) and a control group without PDA (n = 50) who were hospitalized in the neonatal intensive care unit were retrospectively evaluated. The characteristics, perinatal factors, N/L ratio, platelet counts and other platelet indices of the infants in both groups during the first 3 days of life were recorded.
RESULTS: Platelet counts were significantly lower in the patient group than in the control group (p = 0.0343). There was a marked positive correlation between body weight and N/L ratio in preterm infants with PDA (p = 0.0001). PDA was associated with low platelet count.
CONCLUSION: Our results showed that N/L ratio is positively correllated with body weight in PDA group. These data suggest that platelet counts and N/L ratio might be useful predictors for the early diagnosis and evaluation of the clinical course of PDA in preterm infants (Tab. 2, Ref. 28).

Keywords: correlation, ductus arteriosus, neutrophil to lymphocyte ratio, platelet count, preterm infant
Published online: 31-Aug-2017
Year: 2017, Volume: 118, Issue: 8 Page From: 491, Page To: 494
doi:10.4149/BLL_2017_094


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