Home Bratislava Medical Journal 2017 Bratislava Medical Journal Vol.118, No.9, p.529-534, 2017

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Published Monthly, in English
Founded: 1919
ISSN 0006-9248
(E)ISSN 1336-0345

Impact factor 1.564


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Bratislava Medical Journal Vol.118, No.9, p.529-534, 2017

Title: Bone metastases in neuroendocrine tumors
Author: R. Zamborsky, A. Svec, M. Kokavec, S. Galbavy

Abstract: Neuroendocrine tumors arise from various cells that form a part of the endocrine system and account for a small number of cases encountered by oncologists in clinical practice. The clinical incidence of these tumors used to be low, and newer imaging modalities have now begun to be used for detecting bone metastases at an earlier stage. Bone metastases arising from neuroendocrine tumors are a well-recognized complication. Their presence carries along a poor prognosis. Clinical symptoms are similar to those encountered in other forms of cancer that are complicated by bone metastasis. Over the last decade or so, the clinical detection, diagnostic methods and treatment strategies have changed dramatically, and new treatments are emerging slowly. The indolent course of neuroendocrine tumors and the development of bone metastasis have limited our current knowledge on how to best prevent and manage the condition. Current information available from clinical studies is marred by paucity and small sample sizes, making further clinical trials an absolute necessity. In this review, we discuss the current status in the diagnosis and management of bone metastases arising from neuroendocrine tumors (Fig. 3, Ref. 28).

Keywords: endocrine tumors, metastatic tumor/carcinoma, neoplasm metastasis, bone metastasis, biomarkers, diagnostic imaging, bone resection
Published online: 18-Oct-2017
Year: 2017, Volume: 118, Issue: 9 Page From: 529, Page To: 534

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