Home Bratislava Medical Journal 2018 Bratislava Medical Journal Vol.119, No.3, p.175-179, 2018

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Published Monthly, in English
Founded: 1919
ISSN 0006-9248
(E)ISSN 1336-0345

Impact factor 1.564


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Bratislava Medical Journal Vol.119, No.3, p.175-179, 2018

Title: Selected physicochemical properties of amniotic fluid according to week of pregnancy
Author: B. Velika, A. Birkova, R. Dudic, P. Urdzik, M. Marekova


BACKGROUND: A hundred years ago, scientists believed that amniotic fluid is a yellowish hypotonic mixture of foetal urine and maternal transudate with peculiar odour. Current knowledge shows that it represents a dynamic, complex mixture of inorganic and organic compounds.
OBJECTIVES: Despite modern technological procedures, information is still lacking about the composition and properties of amniotic fluid. We focused on dynamics of selected physical and chemical properties of the amniotic fluid with the increasing gestational week.
METHODS: The physicochemical characteristics of 89 amniotic fluid samples were determined according to the week of pregnancy. The determination of pH, specific gravity, glucose and nitrites was performed immediately, at room temperature.
RESULTS: Our results show a significant negative correlation between week of pregnancy and semi-quantitative determined parameters of specific gravity (p < 0.001), pH (p < 0.01) and glucose (p < 0.001) values. Within the whole group of samples (n = 89), 29 % (n = 26) were nitrites positive (N+) and 71 % (n = 63) nitrites negative (N–).

CONCLUSION: In this study were determined basic parameters of amniotic fluid, which could be related to a wide range of pathological states (Tab. 2, Fig. 1, Ref. 27).

Keywords: amniotic fluid, gestational week, physicochemical properties, pregnancy
Published online: 06-Mar-2018
Year: 2018, Volume: 119, Issue: 3 Page From: 175, Page To: 179

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