Journal info
|
||
Select Journal
Journals
Bratislava Medical Journal Endocrine Regulations General Physiology and Biophysics Neoplasma 2024 Ahead of print 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 Acta Virologica Studia Psychologica Cardiology Letters Psychológia a patopsych. dieťaťa Kovove Materialy-Metallic Materials Slovenská hudbaWebshop Cart
Neoplasma Vol.65, No.2, p.178-184, 2018 |
||
Title: The association between LncRNA HOTAIR and cancer lymph node metastasis and distant metastasis: a meta-analysis | ||
Author: Z. SUN, X. Y. WU, C. L. WU | ||
Abstract: HOTAIR has been reported to be associated with development and metastasis in different types of cancer. This meta- analysis collected all relevant articles and explored the correlation of HOTAIR with lymph node metastasis (LNM) and distant metastasis (DM). A literature collection was conducted by searching PubMed, Web of Science, Google Scholar and Cochrane Library (up to Sep 11, 2016). The odds ratio (OR) with 95% confidence interval (95% CI) was calculated to assess the association with strength. Nineteen studies were included in this study, with a total of 1874 patients. The study objects were all Asians. We found high HOTAIR expression in tumor tissues was significantly correlated with LNM and DM, and analysis showed a pooled OR of 3.18 (95% CI: 2.10–4.81, p<0.00001) and 3.93 (95% CI: 2.39–6.47, p<0.00001), respectively. HOTAIR may serve as a novel diagnostic biomarker for cancer metastasis. |
||
Keywords: HOTAIR, lymph node metastasis, distant metastasis, meta-analysis | ||
Published online: 13-Mar-2018 | ||
Year: 2018, Volume: 65, Issue: 2 | Page From: 178, Page To: 184 | |
doi:10.4149/neo_2018_170114N34 |
||
|
download file |
|