Home Bratislava Medical Journal 2018 Bratislava Medical Journal Vol.119, No.4, p.217-220, 2018

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Published Monthly, in English
Founded: 1919
ISSN 0006-9248
(E)ISSN 1336-0345

Impact factor 1.2

 

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Bratislava Medical Journal Vol.119, No.4, p.217-220, 2018

Title: Immunosenescence – the role in the immunotherapy of older population
Author: M. Prcina, M. Novak, V. Cigankova, E. Kontsekova

Abstract: With ageing of their populations, many societies are challenged with serious systemic diseases. One of the causes of these diseases could be the age-related defects in immune system termed immunosenescence. Immunosenescence is characterized by accumulation of memory and non-functional immune cells, impaired signalling due to restricted repertoire of receptors, overall pro-inflammatory environment and complete dysregulation of the immune system. Consequences of immunosenescence are serious, older people are not able to respond to new stimuli, including infections and vaccinations and are more prone to oncologic, neurodegenerative and autoimmune diseases (Ref. 49).

Keywords: immunosenescence, vaccination, neurodegeneration
Published online: 09-Apr-2018
Year: 2018, Volume: 119, Issue: 4 Page From: 217, Page To: 220
doi:10.4149/BLL_2018_040


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