Home CONTACT Neoplasma 2018 Neoplasma Vol.65, No.3, p.389-397, 2018

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Founded: 1954
ISSN 0028-2685
ISSN 1338-4317 (online)

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Neoplasma Vol.65, No.3, p.389-397, 2018

Title: Multiparametric MRI analysis of morphologico-functional features of DCIS – correlation with the grade of nuclear atypia

Abstract: The aim was to analyze morphologico-functional characteristics of ductal carcinoma in situ (DCIS) in breast MRI to assess signs correlating with the degree of nuclear atypia. From 636 malignant lesions, 114 were DCIS (17.92%): 44 cases  of high-grade (38.60%), 37 intermediate (32.45%), 33 low-grade (28.95%). MRI characteristics – T2 signal intensity (SI), shape, margins, contrast enhancement, peripheral/ductal enhancement, kinetic curve, presence of restriction of diffusion were correlated with the nuclear grade of DCIS. Statistical analysis was performed, statistical significance and Odds ratio (OR) were calculated. Signs of high-grade lesions were low SI in T2w (p=0.042), nonhomogeneous contrast enhancement (p=0.012), wash-out phenomenon (p=0.04), high SI in diffusion weighted imaging (DWI) (p

Keywords: breast carcinoma, ductal carcinoma in situ, multiparametric magnetic resonance imaging, diffusion weighted imaging, tumor grading
Published online: 16-May-2018
Year: 2018, Volume: 65, Issue: 3 Page From: 389, Page To: 397

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