Neoplasma Vol.65, No.4, p.592-598, 2018
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| Title: Adjuvant chemotherapy provided survival benefit for stage T2N0 gastric cancer with high-risk factors |
| Author: Z. WANG, J. YAN, W. HU, J. ZHANG, B. HUO |
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Abstract: The value of adjuvant chemotherapy in T2N0 gastric cancer (GC) remains controversial. The aim of this retrospective study is to define a high-risk subgroup of pathological T2N0 GC patients and examine the impact of adjuvant chemotherapy on overall survival (OS). A total of 225 patients underwent R0 resection for T2N0 gastric adenocarcinoma between 2002 and 2012 and 51/225 (22.7%) of these received adjuvant chemotherapy. Multivariate Cox regression identified tumor location in the Upper1/3 of the stomach (peast one of the independent risk factor listed above, and we found that adjuvant chemotherapy significantly improved OS for this subgroup.
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| Keywords: gastric cancer, adjuvant chemotherapy, prognosis, propensity score matching |
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Published online: 30-Jul-2018
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| Year: 2018, Volume: 65, Issue: 4 |
Page From: 592, Page To: 598 |
doi:10.4149/neo_2018_170620N436
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