Home General Physiology and Biophysics 2018 General Physiology and Biophysics Vol.37, No.4, p.469–473, 2018

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Founded: 1982
ISSN  1338-4325 (online)

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General Physiology and Biophysics Vol.37, No.4, p.469–473, 2018

Title: Effect of melatonin on the behaviour of rats with continuous light-induced hypertension
Author: K. Repova, K. Krajcirovicova, M. Mullerova, S. Aziriova, T. Baka, S. Zorad, P. Slavkovsky, J. Hodosy, P. Celec, M. Adamcova, L. Paulis, F. Simko

Abstract: This study investigated whether continuous light exposure (CLE) results in behavioural disturbances in rats and whether melatonin can modify these potential changes. Four groups of 3-month-old Wistar rats were treated as follows for six weeks: control, melatonin, CLE, and CLE with melatonin. CLE increased systolic blood pressure and melatonin reduced it. No changes in behavioural patterns by CLE were observed. In the controls, melatonin reduced both exploration and locomotion but these parameters remained uninfluenced in the CLE. We conclude that melatonin exerted a different impact on behaviour in controls and in the CLE group.

Keywords: Melatonin, Behaviour, Continuous light, Hypertension
Published online: 17-Jul-2018
Year: 2018, Volume: 37, Issue: 4 Page From: 469, Page To: 473
doi:10.4149/gpb_2017061
Price: 10.00 €






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