Home HOME Acta Virologica 2018 Acta Virologica Vol.62, No.4, p.455-458, 2018

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Founded: 1957
ISSN 0001-723X
E-ISSN 1336-2305

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Acta Virologica Vol.62, No.4, p.455-458, 2018

Title: Similar antibody response observed in single-dose-vaccination vs. revaccination against Aujeszky's disease in wild boar
Author: D. Risco, P. Gonçalves, R. Cerrato, P. Fernández-Llario

Abstract: Wild boar is an important reservoir of Aujeszky's disease virus (ADV). There is concern that transmission of this virus from wild boar to domestic pigs is possible. The aim of this work was to compare the antibody response produced by single dose of a gE-deleted ADV vaccine in wild boar to revaccinated animals, to assess if simple single-dose vaccination plans should be examined as a possible control measure against ADV in wild boar. Twenty-five wild boar (ages ranging between 2.5 to 5 months) were included in this study and distributed in three different groups: a control group (n = 5), a single-dose group (10 animals vaccinated only with one dose (day 0)) and a revaccinated group [10 animals vaccinated (day 0) and revaccinated (day 28)]. Mean antibody titers against ADV were determined in three groups using an ELISA assay at three different time points [day 0 (pre-vaccination), 28 (post 1st dose) and 56 (post 2nd dose)]. At day 28, single-dose and revaccinated groups showed a significant increment of antibody titers whereas antibodies in the control group remained stable. At day 56, revaccinated animals did not show a significant increment and antibody titers were similar to those found in animals vaccinated with one dose. These results indicate that vaccination with one dose produces a similar early antibody response to revaccination and therefore, should be examined as a possible control measure against ADV in wild boar.

Keywords: Aujeszky's disease; serology; vaccination; wild boar
Published online: 23-Nov-2018
Year: 2018, Volume: 62, Issue: 4 Page From: 455, Page To: 458

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