Home Neoplasma 2019 Neoplasma Vol.66, No.2, p.245-251, 2019

Journal info

6 times a year.
Founded: 1954
ISSN 0028-2685
ISSN 1338-4317 (online)

Published in English

Editorial Info
Abstracted and Indexed
Submission Guidelines

Select Journal

Webshop Cart

Your Cart is currently empty.

Info: Your browser does not accept cookies. To put products into your cart and purchase them you need to enable cookies.

Neoplasma Vol.66, No.2, p.245-251, 2019

Title: Expression profile of long noncoding RNAs in human papillary thyroid carcinoma
Author: Y. Cao, C. Shi, J. Li, Y. Liang, J. Qiu, L. Yuan, Z. Yong, D. X. Zhang, G. Q. Shi

Abstract: Long non-coding RNAs (lncRNAs) are strongly associated with cancer biology. The objective of this study is to investigate the expression profile of lncRNAs in human papillary thyroid carcinoma (PTC), and to understand the biological role of lncRNAs and their involvement in PTC oncogenesis. The lncRNAs and messenger RNAs (mRNAs) expression in human PTC and paired adjacent non-cancerous thyroid (NCT) tissues were studied by micro-array, and quantitative real-time polymerase chain reaction (qRT-PCR) validated five differentially expressed lncRNAs. We identified 2,925 significantly differentially expressed lncRNAs with potential roles in PTC, (absolute fold change >2.0; pnesis and provide understanding of the function and mechanism of lncRNAs related to human papillary thyroid carcinoma.

Keywords: Papillary thyroid carcinoma, long noncoding RNAs, mRNA, micro-array
Published online: 19-Mar-2019
Year: 2019, Volume: 66, Issue: 2 Page From: 245, Page To: 251

download file

© AEPress s.r.o
Copyright notice: For any permission to reproduce, archive or otherwise use the documents in the ELiS, please contact AEP.