Home Bratislava Medical Journal 2019 Bratislava Medical Journal Vol.120, No.4, p.316–319 2019

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Published Monthly, in English
Founded: 1919
ISSN 0006-9248
(E)ISSN 1336-0345
 

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Bratislava Medical Journal Vol.120, No.4, p.316–319 2019

Title: Is serum uric acid a predictive factor for stroke in men with hypertriglyceridemia?
Author: Y. J. Lai, C. Y. Hsu

Abstract: OBJECTIVE: This study investigated the association between serum uric acid (sUA) and stroke risk in men with hypertriglyceridemia.
METHODS: Between 2002 and 2012, male patients with pure hypertriglyceridemia and a triglyceride (TG) level ≥ 150 mg/dL were enrolled. Eligible patients were categorized into two groups according to their sUA levels (≥ and < 8 mg/dL). Clinical characteristics and comorbidities that are risk factors for stroke were recorded and compared between the groups.
RESULTS: A total of 265 male patients (95 with sUA ≥ 8 mg/dL and 170 with sUA < 8 mg/dL) were enrolled. The incidence of ischemic type of stroke was significantly higher in patients with sUA ≥ 8 mg/dL (p = 0.038), particularly in the age range of 45–65 years. Multivariate Cox proportional analyses confirmed that age (p = 0.003) and UA (p = 0.019) were major predictive factors for stroke free (ischemic type of stroke) survival.
CONCLUSION: Among men with hypertriglyceridemia, the incidence rate of ischemic type of stroke significantly increased with sUA levels ≥ 8 mg/dL, particularly in men aged 45 to 65 years. Hyperuricemia is considered a potential predictive factor for ischemic type of stroke and may indicate the need for preventive management in patients with hypertriglyceridemia (Tab. 3, Fig. 1, Ref. 28).

Keywords: hypertriglyceridemia, hyperuricemia, stroke
Published online: 26-Apr-2019
Year: 2019, Volume: 120, Issue: 4 Page From: 316, Page To: 319
doi:10.4149/BLL_2019_043


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