Home HOME Neoplasma 2019 Neoplasma Vol.66, No.5, p.810–817, 2019

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Neoplasma Vol.66, No.5, p.810–817, 2019

Title: The prognostic value of the 8th edition of the American Joint Committee on Cancer (AJCC) staging system in triple-negative breast cancer
Author: J. P. LI, X. M. ZHANG, Y. S. ZHANG, L. H. ZHENG, Y. J. LIU

Abstract: The American Joint Committee on Cancer (AJCC) released its 8th edition of cancer staging implemented in early 2018. This study aims to compare anatomic staging (AS) with prognostic staging (PS) based on the updated AJCC 8th edition staging manual. A retrospective single-center analysis of 313 triple-negative breast invasive ductal carcinoma patients who received surgery at department of breast surgery in the Fourth Hospital of Hebei Medical University from 01/2010 -12/2012 was performed. All cases were restaged using the AJCC 8th edition AS and PS system. The 7-year disease-free survival (DFS) and the 7-year overall survival (OS) rates were 76.30% and 78.27%, respectively. Applying the PS system, 277 (88.5%) patients of the AS groups were upstaged to the PS groups, 31 cases with IIIC and 5 cases with IV unchanged (11.5%) and no cases downstaged. Both 7-year DFS and 7-year OS were significantly different in the different AS and PS groups (all, p

Keywords: American Joint Committee on Cancer, anatomic stage, prognostic stage, TNBC
Published online: 30-Sep-2019
Year: 2019, Volume: 66, Issue: 5 Page From: 810, Page To: 817

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