Home Neoplasma 2019 Neoplasma Vol.66, No.6, p.988–994, 2019

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Founded: 1954
ISSN 0028-2685
ISSN 1338-4317 (online)

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Neoplasma Vol.66, No.6, p.988–994, 2019

Title: Survival rate of colon and rectum cancer in Iran: A systematic review and meta-analysis
Author: M. H. Panahi, H. Panahi, A. Mahdavi Hezaveh, M. A. Mansourni, R. Bidhendi Yarandi

Abstract: Colorectal cancer is one of the deadliest cancers worldwide. Effective screening, surveillance and prevention can decrease its incidence, mortality and burden. This meta-analysis aims to provide a pooled estimation of 5-year survival rate for colorectal cancer based on topography codes and treatment in Iranian population. A systematic search for literature was done in international and national databases up to July 2018. Twenty-seven studies from 4929 articles met the eligible criteria. The overall pooled 5-year survival rates of colorectal cancer, colon, rectal and sigmoid were 56% (95% CI: 49, 63), 53% (95% CI: 41, 65), 52% (95% CI: 41, 62) and 38% (95% CI: 22, 55), respectively. In addition, 5-year survival rate of colorectal cancer after surgery was 64% (95%CI: 50, 78). Subgroup analysis by type of data source showed significantly higher rate of survival in oncology center (29%) than hospital-based (p=0.005). As a conclusion, low survival rate of colorectal cancer in Iran necessitates effective screening and surveillance strategies to find precancerous polyps and detect early-stage cases with lower stage risk of cancer.

Keywords: survival rate, colorectal neoplasms, meta-analysis
Published online: 13-Oct-2019
Year: 2019, Volume: 66, Issue: 6 Page From: 988, Page To: 994

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