Journal info
|
||
Select Journal
Journals
Bratislava Medical Journal Endocrine Regulations General Physiology and Biophysics Neoplasma 2024 Ahead of print 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 Acta Virologica Studia Psychologica Cardiology Letters Psychológia a patopsych. dieťaťa Kovove Materialy-Metallic Materials Slovenská hudbaWebshop Cart
Your Cart is currently empty.
Info: Your browser does not accept cookies. To put products into your cart and purchase them you need to enable cookies.
Neoplasma Vol.67, No.1, p.185–192, 2020 |
||
Title: Chromosomal aberrations in ascetic fluid of metastatic gastric cancer patients: A clustering analysis | ||
Author: T. Nayebbagher, H. Pashaiefar, M. Yaghmaie, K. Alimoghaddam, M. Jalili, M. Esfandbod, M. Saberian, H. Behroozi, M. Izadifard, A. Ghavamzadeh | ||
Abstract: To date, no specific pattern of chromosomal abnormalities has been established in gastric cancer (GC). Cytogenetic analysis was performed using G-banding and fluorescence in situ hybridization (FISH) in 9 ascetic fluids from GC patients, and the clustering patterns of chromosomal abnormalities were studied. Twenty-six different types of chromosomal abnormalities were identified. In contrast to structural abnormalities, the gain or loss of chromosomes was infrequent. Moreover, five main clusters of chromosomal abnormalities were identified by clustering analysis. Extensive cytogenetic complexity, specific chromosomal abnormalities and karyotype heterogeneity are the main characterizations of GC. Some of the recurrent and novel chromosomal abnormalities with distinct clustering patterns identified in this study may play important roles for GC initiation and progression and could serve as promising diagnostic and prognostic markers in GC patients. |
||
Keywords: chromosomal abnormalities, ascetic fluids, clustering analysis, gastric cancer | ||
Published online: 29-Jan-2020 | ||
Year: 2020, Volume: 67, Issue: 1 | Page From: 185, Page To: 192 | |
doi:10.4149/neo_2019_190202N105 |
||
|
download file |
|