Home FOR AUTHORS Neoplasma 2020 Neoplasma Vol.67, No.1, p.185–192, 2020

Journal info


6 times a year.
Founded: 1954
ISSN 0028-2685
ISSN 1338-4317 (online)

Published in English

Editorial Info
Abstracted and Indexed
Submission Guidelines

Select Journal







Webshop Cart

Your Cart is currently empty.

Info: Your browser does not accept cookies. To put products into your cart and purchase them you need to enable cookies.

Neoplasma Vol.67, No.1, p.185–192, 2020

Title: Chromosomal aberrations in ascetic fluid of metastatic gastric cancer patients: A clustering analysis
Author: T. Nayebbagher, H. Pashaiefar, M. Yaghmaie, K. Alimoghaddam, M. Jalili, M. Esfandbod, M. Saberian, H. Behroozi, M. Izadifard, A. Ghavamzadeh

Abstract: To date, no specific pattern of chromosomal abnormalities has been established in gastric cancer (GC). Cytogenetic analysis was performed using G-banding and fluorescence in situ hybridization (FISH) in 9 ascetic fluids from GC patients, and the clustering patterns of chromosomal abnormalities were studied. Twenty-six different types of chromosomal abnormalities were identified. In contrast to structural abnormalities, the gain or loss of chromosomes was infrequent. Moreover, five main clusters of chromosomal abnormalities were identified by clustering analysis. Extensive cytogenetic complexity, specific chromosomal abnormalities and karyotype heterogeneity are the main characterizations of GC. Some of the recurrent and novel chromosomal abnormalities with distinct clustering patterns identified in this study may play important roles for GC initiation and progression and could serve as promising diagnostic and prognostic markers in GC patients.

Keywords: chromosomal abnormalities, ascetic fluids, clustering analysis, gastric cancer
Published online: 29-Jan-2020
Year: 2020, Volume: 67, Issue: 1 Page From: 185, Page To: 192
doi:10.4149/neo_2019_190202N105


download file



© AEPress s.r.o
Copyright notice: For any permission to reproduce, archive or otherwise use the documents in the ELiS, please contact AEP.