Home FOR AUTHORS Bratislava Medical Journal 2019 Bratislava Medical Journal Vol.120, No.12, p.894–898, 2019

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Published Monthly, in English
Founded: 1919
ISSN 0006-9248
(E)ISSN 1336-0345

Impact factor 1.564

 

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Bratislava Medical Journal Vol.120, No.12, p.894–898, 2019

Title: Central systolic blood pressure increases with aortic stiffness
Author: J. Bulas, M. Potocarova, V. Kupcova, L. Gaspar, G. Wimmer, J. Murin

Abstract: OBJECTIVES: Central systolic blood pressure (CSBP) is the pressure in the root of aorta, which directly influences organs such as brain, heart and kidneys and is related to organ damage. Its value increases with the aortic stiffness. The aim of this study was to analyze the relationships of CSBP to aortic stiffness parameters.
METHODS: Central blood pressure (BP) and related parameters were measured by Arteriograph, working based on oscillometric principle, using pulse wave analysis (PWA) approach. We examined 123 patients (69 females, 54 males) with a primary hypertension.
RESULTS: Using a linear correlation analysis, we found that CSBP was correlated to aortic pulse wave velocity (PWV), aortic and brachial pulse pressure (PP), aortic augmentation index, return time of reflected pressure wave (RT) and aortic and brachial augmentation indexes. Multivariate analysis defines the aortic pulse pressure (PPao) as the most powerful parameter influencing CSBP. By an individual analysis of BP in each patient separately, we defined two different types of central hemodynamics; those with a higher CSBP than brachial SBP occur in stiffer aorta.
CONCLUSION: The CSBP increases with aortic PP, the most powerful stiffness parameter of aorta. Higher CSBP than brachial SBP usually accompanies a stiffer aorta (Tab. 5, Ref. 19).

Keywords: central systolic pressure, aortic stiffness, augmentation index
Published online: 18-Dec-2019
Year: 2019, Volume: 120, Issue: 12 Page From: 894, Page To: 898
doi:10.4149/BLL_2019_150


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