Acta Virologica Vol.64, No.2, p.251-260, 2020

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Founded: 1957
ISSN 0001-723X
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Acta Virologica Vol.64, No.2, p.251-260, 2020
Title: Recent advances in vaccines and diagnostics against Middle East respiratory syndrome coronavirus
Author: K. LEE, J. H. NAM

Abstract: Middle East respiratory syndrome coronavirus (MERS-CoV) is an RNA virus that causes severe respiratory disease. Since it was identified in 2012, approximately 2500 MERS cases with high mortality have been confirmed in 27 countries. Although most cases have occurred in the Middle East, an outbreak in South Korea in 2015 showed that MERS could be a global threat via human-to-human transmission. There is no licensed vaccine against MERS. Thus, early detection is the best way to limit the spread of this fatal disease. In this review, we focus on transmission, the infection process, and scientific efforts in vaccine development and diagnostics for MERS-CoV.

Keywords: Middle East respiratory syndrome coronavirus; epidemiology; virology; vaccine; diagnostics
	Published online: 08-Apr-2020
Year: 2020, Volume: 64, Issue: 2	Page From: 251, Page To: 260
doi:10.4149/av_2020_208
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