Home Bratislava Medical Journal 2020 Bratislava Medical Journal Vol.121, No.5, p.366–369,2020

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Published Monthly, in English
Founded: 1919
ISSN 0006-9248
(E)ISSN 1336-0345

Impact factor 1.564


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Bratislava Medical Journal Vol.121, No.5, p.366–369,2020

Title: A possible connection between circulating 25-hydroxy-vitamin D and molecular response in chronic myeloid leukemia
Author: F. Gediz, G. G. Oruk, U. B. Korkmaz, S. Aksun, M. Calan, K. Savasoglu, A. F. Yilmaz, K. B. Payzin

Abstract: OBJECTIVE: In this study we aimed to evaluate whether there is a link between circulating 25-OH-D levels and molecular response in chronic myeloid leukemia (CML).
MATERIAL AND METHOD: A total of 61 patients with CML (31 women, 30 men) were recruited in this cross-sectional study.
RESULTS: Binary logistic regression analysis demonstrated that increased vitamin D levels were independently associated with molecular response in subjects with CML.
CONCLUSION: Our results indicated for the first time in the literature that severe deficiency of vitamin D was independently associated with molecular unresponsiveness in subjects with CML. 25-OH-D may be contributing to molecular response in the patients (Tab. 3, Ref. 24).

Keywords: chronic myeloid leukemia, vitamin D deficiency, molecular response.
Published online: 29-Apr-2020
Year: 2020, Volume: 121, Issue: 5 Page From: 366, Page To: 369

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