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Bratislava Medical Journal 2020 Bratislava Medical Journal Vol.121, No.5, p.366–369,2020
Bratislava Medical Journal 2020 Bratislava Medical Journal Vol.121, No.5, p.366–369,2020
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Bratislava Medical Journal Vol.121, No.5, p.366–369,2020 |
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| Title: A possible connection between circulating 25-hydroxy-vitamin D and molecular response in chronic myeloid leukemia | ||
| Author: F. Gediz, G. G. Oruk, U. B. Korkmaz, S. Aksun, M. Calan, K. Savasoglu, A. F. Yilmaz, K. B. Payzin | ||
| Abstract: OBJECTIVE: In this study we aimed to evaluate whether there is a link between circulating 25-OH-D levels and molecular response in chronic myeloid leukemia (CML). MATERIAL AND METHOD: A total of 61 patients with CML (31 women, 30 men) were recruited in this cross-sectional study. RESULTS: Binary logistic regression analysis demonstrated that increased vitamin D levels were independently associated with molecular response in subjects with CML. CONCLUSION: Our results indicated for the first time in the literature that severe deficiency of vitamin D was independently associated with molecular unresponsiveness in subjects with CML. 25-OH-D may be contributing to molecular response in the patients (Tab. 3, Ref. 24). |
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| Keywords: chronic myeloid leukemia, vitamin D deficiency, molecular response. | ||
| Published online: 29-Apr-2020 | ||
| Year: 2020, Volume: 121, Issue: 5 | Page From: 366, Page To: 369 | |
| doi:10.4149/BLL_2020_059 |
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