Home Bratislava Medical Journal 2020 Bratislava Medical Journal Vol.121, No.10, p.733–741,2020

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Published Monthly, in English
Founded: 1919
ISSN 0006-9248
(E)ISSN 1336-0345

Impact factor 1.2

 

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Bratislava Medical Journal Vol.121, No.10, p.733–741,2020

Title: Coronaviruses as the emerging threats for human health: should we be prepared for the future outbreaks of new coronaviruses?
Author: R. Bahrami, D. Hashemi, S. Keshavarz Aziziraftar, P. Rahimi

Abstract: Recent emergence of SARS-CoV-2 in human communities as the first major zoonotic pandemics of the new millennium following the emergence of SARS-CoV and MERS-CoV has increased our awareness about the future threat of viral zoonosis. Although, several studies have been conducted for better understanding of these viruses` evolution, and designing the effective anti-viral drugs and vaccines, the impact of human beings on occurrence of zoonotic diseases has been less considered and discussed. Improvement in global health resulted in human population growth, increasing demand for animal proteins, more exposures to wildlife, zoonotic and degradation of environment, which have facilitated interspecies transmissions. Since world population is increasing proportionately, the protection of public health against zoonotic diseases is a challenging task. It seems that intensified revision of human lifestyle is the best strategy to prevent the potential devastating future zoonotic pandemics. Herein, the characteristics of SARS-CoV, MERS-CoV, SARS-CoV-2, their transmission routs, their pathogenicity, the therapeutic and prevention approaches including of attempts for designing of effective prophylactic vaccines, anti-viral drugs, and the animal models that have been used for these studies have been reviewed (Ref. 134).

Keywords: SARS-CoV-2, COVID-19, pandemic, zoonosis, SARS, MERS
Published online: 20-Sep-2020
Year: 2020, Volume: 121, Issue: 10 Page From: 733, Page To: 741
doi:10.4149/BLL_2020_120


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