Journal info
|
||||
Select Journal
Journals
Bratislava Medical Journal 2024 Ahead of print 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 Endocrine Regulations General Physiology and Biophysics Neoplasma Acta Virologica Studia Psychologica Cardiology Letters Psychológia a patopsych. dieťaťa Kovove Materialy-Metallic Materials Slovenská hudbaWebshop Cart
Your Cart is currently empty.
Info: Your browser does not accept cookies. To put products into your cart and purchase them you need to enable cookies.
Bratislava Medical Journal Vol.122, No.1, p.49–55,2021 |
||
Title: Red blood cell distribution width is a predictor of chronic kidney disease progression and all-cause mortality | ||
Author: F. Yilmaz, H. Sozel | ||
Abstract: OBJECTIVES: The aim of this study was to investigate the association of RDW with all-cause mortality and disease progression in patients with CKD in stage 3–4. METHODS: This longitudinal observational cohort study of patients with CKD was conducted at a single center. We categorized baseline RDW into two groups by its median (14.9 %). The associations between baseline RDW values and all-cause mortality over 56 months were examined in unadjusted and adjusted models. The effect of RDW value on renal outcomes and mortality was evaluated by using Cox regression analysis. RESULTS: A total of 261 patients were enrolled in the study. During an average follow-up of 56 months, 19.8 % of patients died. The area under the ROC curve for RDW for all-cause mortality was 0.746, with sensitivity of 0.74 and specificity of 0.69 for a cut-off point of 14.3 %. The incidence of all-cause mortality in the group with increased RDW was significantly higher than in the normal RDW group (p < 0.001). The Cox proportional hazard model showed that the elevated RDW level was an independent risk factor for all-cause mortality in patients with CKD in stage 3–4. CONCLUSION: RDW is a powerful and independent prognostic marker for predicting all-cause mortality and disease progression in stage 3–4 of CKD (Tab. 4, Fig. 4, Ref. 29). |
||
Keywords: chronic kidney disease, red blood cell distribution width, mortality, progression | ||
Published online: 04-Jan-2021 | ||
Year: 2021, Volume: 122, Issue: 1 | Page From: 49, Page To: 55 | |
doi:10.4149/BLL_2021_006 |
||
|
download file |
|