Home Bratislava Medical Journal 2021 Bratislava Medical Journal Vol.122, No.6, p.418–423,2021

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Published Monthly, in English
Founded: 1919
ISSN 0006-9248
(E)ISSN 1336-0345

Impact factor 1.564


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Bratislava Medical Journal Vol.122, No.6, p.418–423,2021

Title: Comparison of inflammation markers with prediction scores in patients with community-acquired pneumonia
Author: E. Acar, H. Gokcen, A. Demir, B. Yildirim

Abstract: OBJECTIVE: The lymphocyte-to-C-reactive protein ratio (LCRP) and Systemic Immune-Inflammation Index (SII) can successfully predict 28-day mortality rates with community-acquired pneumonia
METHODS: This prospective study was conducted in 2018. Hospitalized patients underwent follow-up evaluations 28 days after admission.
RESULTS: A total of 345 patients with CAP were enrolled in this study. All-cause mortality at the 28th day of follow-up was 13.6 %. There were statistically significant results between the 2 groups (survivors and non-survivors), in terms of the LCRP, SII, PSI, and CURB-65 values. Moreover, the optimal LCRP cutoff for predicting 28-day mortality was determined to be 4, with 89 % sensitivity, 73 % specificity. Based on the average SII>3551for predicting 28-day mortality, the sensitivity, specificity was 63.8 %, 68.1 % respectively. When the value of the cutoff PSI was ≥130 points, the sensitivity, specificity was 68 %, 65 %, respectively. Based on 3 points and above as the cutoff value of the CURB-65 score, the sensitivity, specificity was 80 %, 68 %, respectively.
ROC curve analysis revealed that the areas of LCRP, SII, PSI, and CURB-65 under the AUC in terms of 28-day mortality were 0,820,0,737,681, and 0,773, respectively,
CONCLUSIONS: LCRP and SII level are valuable for predicting the mortality rate among patients with CAP at ED admission (Tab. 3, Fig. 3, Ref. 27).

Keywords: community-acquired pneumonia, respiratory tract infection, prediction scores, lymphocyte to CRP ratio, systemic immune-inflammation index, mortality
Published online: 18-May-2021
Year: 2021, Volume: 122, Issue: 6 Page From: 418, Page To: 423

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