Home Bratislava Medical Journal 2021 Bratislava Medical Journal Vol.122, No.8, p.555–558,2021

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Published Monthly, in English
Founded: 1919
ISSN 0006-9248
(E)ISSN 1336-0345

Impact factor 1.564

 

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Bratislava Medical Journal Vol.122, No.8, p.555–558,2021

Title: Mortality and risk factors after a surgical repair of postinfarction ventricular septal defect
Author: P. Artemiou, I. Gasparovic, B. Bezak, V. Hudec, I. Glonek, M. Hulman
Abstract: BACKGROUND: The aim of this study was to present our experience in the treatment of post-myocardial infarction ventricular septal defect and examine the various risk factors.
METHODS: This is a retrospective study. From January 2010 to December 2018, 20 patients underwent an urgent /emergency surgical repair of post-myocardial infarction ventricular septal defect.
RESULTS: The mortality in our group of patients was 45 %. Non-survivors compared to the survivors were all in cardiogenic shock (p=0.0098), had an emergency/salvage operation (p=0.0055), preoperative mechanical ventilation (p=0.0081), shorter time between intraaortic balloon pressure insertion and surgery (p=0.0115), shorter median time between ventricular septal defect and surgery, postoperative renal replacement therapy (p=0.0498), and more patients had a residual effect (p=0.0022). In multivariate analysis, preoperative mechanical ventilation (p=0.0001), postoperative renal replacement therapy (p=0.0021) and residual defect (p=0.0000027) were shown to be strong predictors for hospital mortality.
CONCLUSION: This analysis showed that post-myocardial infarction ventricular septal defect repair is a devastating complication and preoperative mechanical ventilation, postoperative renal replacement therapy and residual defect were identified to be the predictors of mortality. Initial stabilization of the patients, when it is possible, and a delayed repair, may improve the outcome of these patients (Tab. 3, Ref. 17).
Keywords: myocardial infarct, mortality and risk factors, surgical repair, postinfarction ventricular septal defect, cardiogenic shock, emergency/salvage operation, preoperative mechanical ventilation
Published online: 20-Jul-2021
Year: 2021, Volume: 122, Issue: 8 Page From: 555, Page To: 558
doi:10.4149/BLL_2021_088


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