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Bratislava Medical Journal 2021 Bratislava Medical Journal Vol.122, No.11, p.763–770,2021
Bratislava Medical Journal 2021 Bratislava Medical Journal Vol.122, No.11, p.763–770,2021
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Bratislava Medical Journal Vol.122, No.11, p.763–770,2021 |
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| Title: Point-of-care diagnosis of COVID-19 disease based on antigen tests | ||
| Author: M. Pohanka | ||
| Abstract: AIMS: This review is focused on the laboratory diagnoses of the coronavirus disease 2019 (COVID-19) by recognizing the antigen of the causative agent SARS-CoV-2 virus. Various antigen tests are available in this moment and these tests are being further developed in order to reach a better diagnostic value. The issue is reviewed in a complex view. METHODS: In this work, a complex survey of the current literature was made. The relevant and recent papers related to antigen tests of COVID-19 are discussed and cited. Basic specifications of the antigen tests and competitive methods were also scrutinized in the current literature. RESULTS: The survey of the current literature (years 2019 ‒ 2021) was made and diagnostic methods like lateral flow tests (lateral flow immunochromatographic assay) and various types of biosensors were specified as tools for COVID-19 diagnosis and their application to be used as a point-of-care test is considered. CONCLUSIONS: Small hand-held assays applicable in the point-of-care conditions for diagnosis of COVID-19 by analysis of SARS-CoV-2 antigen are the means of a growing interest and these means undergo a significant development leading to the improvements of their specifications and applicability to the current praxis. Merit of the assays is discussed in this paper (Tab. 3, Fig. 2, Ref. 109). |
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| Keywords: coronavirus disease 2019; diagnosis; enzyme-linked immunosorbent assay; immunoassay; lateral flow test; SARS-CoV-2 | ||
| Published online: 21-Oct-2021 | ||
| Year: 2021, Volume: 122, Issue: 11 | Page From: 763, Page To: 770 | |
| doi:10.4149/BLL_2021_122 |
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