General Physiology and Biophysics Vol.41, No.2, p. 123

General Physiology and Biophysics Vol.41, No.2, p. 123–131, 2022

Founded: 1982
ISSN 1338-4325 (online)
ISSN 0231-5882 (print)
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General Physiology and Biophysics Vol.41, No.2, p. 123–131, 2022
Title: Electrodermal activity spectral and nonlinear analysis – potential biomarkers for sympathetic dysregulation in autism
Author: Zuzana Visnovcova, Nikola Ferencova, Marian Grendar, Igor Ondrejka, Lucia Bona Olexova, Iveta Bujnakova, Ingrid Tonhajzerova

Abstract: Autism spectrum disorder (ASD) is a neurodevelopmental disease characterized by emotional and social deficits, which can be associated with sympathetic dysregulation. Thus, we aimed to analyze the electrodermal activity (EDA) using time, and novel spectral and nonlinear indices in ASD. The cohort consisted of 45 ASD boys and 45 age-matched controls. EDA was continuously recorded at rest. The EDA indices were evaluated by time-, spectral-, and nonlinear-domain analysis. Our results revealed increased non-specific skin conductance responses, spectral parameters in high and very-high frequency bands, approximate and symbolic information entropy indicating sympathetic overactivity in ASD vs. controls (p

Keywords: Electrodermal activity — Autistic spectrum disorder — Nonlinear analysis — Spectral-domain analysis — Time-domain analysis
	Published online: 11-Apr-2022
Year: 2022, Volume: 41, Issue: 2	Page From: 123, Page To: 131
doi:10.4149/gpb_2022011
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