Home 
HOME Bratislava Medical Journal 2022 Bratislava Medical Journal Vol.123, No.6, p.444–448, 2022
HOME Bratislava Medical Journal 2022 Bratislava Medical Journal Vol.123, No.6, p.444–448, 2022
Journal info
|
||||
Select Journal
Journals
Bratislava Medical Journal 2024 Ahead of print 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 Endocrine Regulations General Physiology and Biophysics Neoplasma Acta Virologica Studia Psychologica Cardiology Letters Psychológia a patopsych. dieťaťa Kovove Materialy-Metallic Materials Slovenská hudbaWebshop Cart
Your Cart is currently empty.
Info: Your browser does not accept cookies. To put products into your cart and purchase them you need to enable cookies.
Bratislava Medical Journal Vol.123, No.6, p.444–448, 2022 |
||
| Title: Are platelet indices promising ratios for predicting pediatric septic shock prognosis? | ||
| Author: Mehmet CELEGEN, Selman KESICI, Sinan YAVUZ, Kubra CELEGEN, Benan BAYRAKCI | ||
| Abstract: OBJECTIVES: The aim of the present study was to determine the prognostic value of thrombocytopenia, platelet indices (MPV/PLT and PDW/PLT) in children with septic shock. BACKGROUND: Septic shock is one of the major causes of mortality among children worldwide. METHODS: A retrospective analysis was made of children admitted to the pediatric intensive care unit between November 2010 and December 2019. Two hundred four children were included; they were diagnosed with septic shock according to the international pediatric sepsis consensus conference criteria. The MPV/platelet ratio and PDW/platelet ratios were estimated as the MPV and PDW values divided by the platelet count on the first three days of hospitalization. The clinical outcome was 28-day mortality. RESULTS: MPV/PLT and PDW/PLT ratios were found to be significantly higher in the non-survivors than survivor (p≤0.001). In the multivariate logistic regression analysis, higher MPV/platelet ratios at 72h (OR: 7.41; 95% CI: 1.25–43.7; p=0.027) and PDW/platelet ratios at 72h (OR: 2.9; 95% CI: 1.13–7.50; p=0.027) were significant risk factors for mortality. CONCLUSIONS: Platelet indices are useful laboratory parameters in septic shock. MPV/PLT and PDW/PLT ratios can be promising reliable markers for 28-day mortality in children with septic shock (Tab. 4, Fig. 1, Ref. 29). |
||
| Keywords: septic shock, mortality, platelet indices, thrombocytopenia, children | ||
| Published online: 16-May-2022 | ||
| Year: 2022, Volume: 123, Issue: 6 | Page From: 444, Page To: 448 | |
| doi:10.4149/BLL_2022_069 |
||
|
|
 download file |
|