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Bratislava Medical Journal 2022 Bratislava Medical Journal Vol.123, No.7, p.463–469, 2022
Bratislava Medical Journal 2022 Bratislava Medical Journal Vol.123, No.7, p.463–469, 2022
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Bratislava Medical Journal Vol.123, No.7, p.463–469, 2022 |
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| Title: Age and sex disparity in infectious complications after kidney transplantation | ||
| Author: Matej VNUCAK, Karol GRANAK, Monika BELIANCINOVA, Juraj MIKLUSICA, Ivana DEDINSKA | ||
| Abstract: kidney transplantation (KT). BACKGROUND: Potent immunosuppression lowers the incidence of acute graft rejection but increases the risk of post-transplant infections. Older adults and females are at high risk of infections leading to poor outcome after KT. MATERIALS: Our analysis consisted of 66 males and 34 females after KT, average age 47.5±12.6 years. RESULTS: Female gender was a RF for the incidence of infection in general (p=0.0054), recurrent (p=0.0239), bacterial (p=0.0125) and mycotic infection (p=0.0103), recurrent bacterial infection (p=0.0258) 1st month after KT, RF for the incidence of infection in general (p=0.0218), bacterial (p=0.0186), mycotic (p=0.0318), recurrent (p=0.0216), recurrent bacterial infection (p=0.0368) from 1st to 6th month after KT and RF for the incidence of bacterial (p=0.0144), single (p=0.0355), recurrent (p=0.0007) and single bacterial infection (p=0.0309) 6 months after KT. Age >60 years was not found as a RF for the incidence of single, repeat infection regarding its aetiology. CONCLUSION: We found significant sex differences in the incidence of single and repeat infections in different time intervals after KT (Tab. 4, Fig. 3, Ref. 31). |
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| Keywords: kidney transplantation, gender disparity, sex disparity, infection, acute kidney rejection | ||
| Published online: 06-Jun-2022 | ||
| Year: 2022, Volume: 123, Issue: 7 | Page From: 463, Page To: 469 | |
| doi:10.4149/BLL_2022_074 |
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