Home General Physiology and Biophysics 2022 General Physiology and Biophysics Vol.41, No.4, p. 339–347, 2022

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Quarterly, 80 pp. per issue
Founded: 1982
ISSN  1338-4325 (online)

Published in English

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General Physiology and Biophysics Vol.41, No.4, p. 339–347, 2022

Title: Toe-lift test: a novel, simple and noninvasive in vivo method for contractile evaluation of tibialis anterior muscle
Author: Chung-Min Tsai, Yu-Chun Lo, Chuang-Yu Lin, Chun-Yin Hou, Ya-Li Huang, Hsi Chang

Abstract: Tibialis anterior (TA) muscle has frequently been used for scientific experiments, particularly for muscle contractile assays, because of its anatomical advantages. However, classical evaluation methods for the TA muscle, such as EMG and force transducer, require experimental skills to acquire reliable results. Furthermore, because sacrificing experimental animals is usually indispensable for both methods, sequential observations cannot be performed. Therefore, developing a simple, objective, and animal friendly evaluation system was warranted. In this article, we introduce a novel, simple, and noninvasive in vivo evaluation method for the TA muscle called the toe-lift test (TLT), which is not only easy to perform but also capable of detecting contractile strength precisely. Because the TLT does not require experimental animal sacrifice, performing assessments over time, such as in sequential observation, is possible. This novel method represents a solution to the need for a simple, noninvasive, and effective method for TA muscle contractile evaluation.


Keywords: Tibialis anterior muscle — Contractile evaluation — Electromyography — Force transducer — Nociceptive withdrawal reflex
Published online: 28-Jul-2022
Year: 2022, Volume: 41, Issue: 4 Page From: 339, Page To: 347
doi:10.4149/gpb_2022022


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