Home Bratislava Medical Journal 2022 Bratislava Medical Journal Vol.123, No.9, p.685–691, 2022

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Published Monthly, in English
Founded: 1919
ISSN 0006-9248
(E)ISSN 1336-0345

Impact factor 1.564


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Bratislava Medical Journal Vol.123, No.9, p.685–691, 2022

Title: Screening diagnosis of dementia in patients following heart failure decompensation is associated with a higher relative wall thickness
Author: Karol NOWAK, Adam STEPIEN, Patrycja FURCZYNSKA, Magdalena ZALEWSKA, Gabriela KANCLERZ, Alicia del Carmen YIKA, Konrad STEPIEN, Jadwiga NESSLER, Jaroslaw ZALEWSKI

Abstract: BACKGROUND: The usefulness of echocardiographic characteristics for dementia prediction in patients with heart failure decompensation (HFD) is not determined. Therefore, we sought to investigate the echocardiographic features of patients with HFD and screening diagnosis of dementia (SDD).
METHODS: 139 patients aged over 65 years were hospitalized with the diagnosis of HFD. Clinical characteristics and echocardiographic characteristics were recorded during hospitalization. SDD was defined based on the result of ALFI– MMSE of <17 points.
RESULTS: Patients with SDD were older (p=0.013), had thicker IVSd (p=0.021), thicker PWd (p=0.005) and had a higher RWT (0.40 vs 0.35, p=0.004) than patients without SDD, without differences in LVMI (p=0.13). There was no correlation between RWT and LVMI (r=−0.01, p=0.88). In the multivariate analysis, an older age (β=−0.116, 95% CI −0.224 – −0.008, p=0.035, per year) and a higher RWT (β=−0.069, 95% CI −0.137 – −0.002, p=0.045, per 0.01) influenced a lower ALFI-MMSE. For a prediction of SDD, the RWT reached the area under a ROC curve of 0.67 (95% CI 0.56–0.77, p=0.004 with sensitivity of 60% and specificity of 70% for RWT of ≥0.375).
CONCLUSIONS: Apart from age, RWT reflecting left ventricular geometry changes but not hypertrophy was independently but moderately associated with SDD in patients following HFD (Tab. 4, Fig. 1, Ref. 35).

Keywords: dementia, heart failure, decompensation, echocardiography, relative wall thickness
Published online: 09-Aug-2022
Year: 2022, Volume: 123, Issue: 9 Page From: 685, Page To: 691

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