General Physiology and Biophysics Vol.42, No.6, p. 539

General Physiology and Biophysics Vol.42, No.6, p. 539–549, 2023

Founded: 1982
ISSN 1338-4325 (online)
ISSN 0231-5882 (print)
Published in English,
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General Physiology and Biophysics Vol.42, No.6, p. 539–549, 2023
Title: The effects of the pulsed magnetic field on sepsis-induced liver tissue injury in rats
Author: Fikret Gevrek, Serkan Yelliand, Serkan Gürgül

Abstract: Sepsis is the host’s response to infection and can lead to severe and life-threatening cases. We aimed to investigate the effects of pulsed magnetic field (PMF) on septic liver tissue injury. A total of 28 adult Wistar albino rats were divided equally into four study groups: Sham, PMF-1, PMF-2, and Sepsis, with seven rats in each. Sepsis was performed using the CLP method. PMF-1 and PMF-2 were exposed to 7.5 Hz and 15 Hz PMF, respectively, for 24 hours. After having their livers removed, liver tissues were analysed using histological techniques. We observed remarkable healing in PMF groups. Apoptotic cells decreased in the PMF-treated groups compared with the Sepsis group (p < 0.05). Immune expressions of Acas-3, Bax, and HIF-1 increased in the Sepsis group, while Bcl-2 expression decreased (p septic liver tissue injury.

Keywords: Apoptosis — Inflammation — Liver — Pulsed magnetic field (PMF) — Sepsis
	Published online: 14-Nov-2023
Year: 2023, Volume: 42, Issue: 6	Page From: 539, Page To: 549
doi:10.4149/gpb_2023026
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