Home FOR AUTHORS Endocrine Regulations 2005 Endocrine Regulations Vol.39, p.1-6, 2005

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Quarterly, 50 pp. per issue 
Founded: 1967
ISSN 1210-0668
E-ISSN 1336-0329

Published in English

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Endocrine Regulations Vol.39, p.1-6, 2005

Title: PEPTIDE HORMONES AND HISTAMINE IN PLASMA AND SYNOVIAL FLUID OF PATIENTS WITH RHEUMATOID ARTHRITIS AND OSTEOARTHROSIS
Author: ROVENSKY J, IMRICH R, RADIKOVA Z, SIMOROVA E, GREGUSKA O, VIGAS M, MACHO L

Abstract: Objectives. Hormones other than adrenal and gonadal steroids may play also a significant role in the pathogenesis of rheumatoid arthritis. The aim of this study was to investigate the levels of selected peptide hormones and histamine in synovial fluid of knee joints and in plasma of patients with rheumatoid arthritis and with osteoarthrosis. Methods. The concentrations of insulin, C-peptide, prolactin, growth hormone, free triiodothyronine (FT3), thyrotropin (TSH), and histamine were determined in synovial fluid and plasma of 27 patients with rheumatoid arthritis (RA) and in 12 patients with osteoarthrosis (OA). Results. The presence of peptide hormones in synovial fluid was demonstrated. The levels of TSH and growth hormone were lower in synovial fluid than in plasma in both groups, while those of prolactin were comparable in synovial fluid and in plasma. The levels of C-peptide (ppathogenesis of RA has to be investigated in further studies and analyses.

Keywords: Peptide hormones – Histamine – Synovial fluid – Rheumatoid arthritis – Osteoarthrosis
Year: 2005, Volume: 39, Issue: 1 Page From: 1, Page To: 6



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