Neoplasma Vol.53, p.444-449, 2006
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Title: Radioimmunoscintigraphy of colorectal carcinomas with three
different radiopharmaceuticals
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Author: V., OBRADOVIC
; V., ARTIKO
; M., PETROVIC
; Ž., LAUSEVIC
; M., STOJKOVIC
; N., PETROVIC
; D., SOBIC-SARANOVIC
; M., VLAJKOVIC
; Z., KRIVOKAPIC
; |
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Abstract: The aim of the study was evaluation of the clinical reliability of
the immunoscintigraphy for the detection of metastases
and recurrences of colorectal carcinomas using three different
radiopharmaceutical substances.
With IMACIS 1, the number of true negative findings (TN) was 4/7
and true positive (TP) 3/7, while in one patient, the results
of immunoscintigraphy significantly influenced the therapeutical
management.
With INDIMACIS 19-9, there were 2/8 TN and 6/8 TP. In three
patients, immunoscintigraphy results influenced patient
further management.
With ONCOSCINT in 2 patients findings were TN, in one FN and in
one FP. In 3 patients, immunoscintigraphy influenced
the management of the patient. Other imaging methods (CT, US, MRI)
have advantage in detection of liver
metastases, while immunoscintigraphy is more specific for the
assessment of reccurences of the abdominal tumors. Thus
immunoscintigraphy should be applied in patients with suggested
recurrences and inconclusive outcome of routine diagnostic
workup.
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Keywords: immunoscintigraphy, colorectal carcinoma
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Year: 2006, Volume: 53, Issue: |
Page From: 444, Page To: 449 |
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