Journal info
|
||
Select Journal
Journals
Bratislava Medical Journal Endocrine Regulations General Physiology and Biophysics Neoplasma Acta Virologica Current articles 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 Studia Psychologica Cardiology Letters Psychológia a patopsych. dieťaťa Kovove Materialy-Metallic Materials Slovenská hudbaWebshop Cart
Your Cart is currently empty.
Info: Your browser does not accept cookies. To put products into your cart and purchase them you need to enable cookies.
Acta Virologica Vol.48, p.263-266, 2004 |
||
Title: HIGH TH1-TYPE CYTOKINE SERUM LEVELS IN PATIENTS WITH INFECTIOUS MONONUCLEOSIS | ||
Author: M.M. CORSI, M. RUSCICA, D. PASSONI, M.G. SCARMOZZINO, E. GULLETTA | ||
Abstract: Most adults are asymptomatically infected with Epstein-Barr virus (EBV). Primary EBV infection is commonly associated with acute infectious mononucleosis (IM). T cell immune activation plays an important role in EBV-associated diseases. IM shows a mainly Th1-type profile, so Th1-type cytokines such as interleukin-2 (IL-2), interferon-g (IFN-g), and lymphotoxin (LT) are moderately enhanced. We measured IL-2 and IFN-g in serum during acute phase of the disease and during convalescence. Sera were collected from 23 IM patients, 13 patients with similar clinical manifestations but without IM, and 10 healthy donors. The levels of IL-2, IFN-g and IL-12 were significantly higher in patients with acute IM than in healthy individuals. IL-2, IFN-g and IL-12 decreased during convalescence. These three cytokines may be useful as sensitive markers of IM during severe illness and its later phases. |
||
Keywords: infectious mononucleosis; interferon-g; interleukin-2; interleukin-12 | ||
Year: 2004, Volume: 48, Issue: | Page From: 263, Page To: 266 | |
|
download file |
|