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Neoplasma Vol.50, p.66-73, 2003 |
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Title: Cavitated tumor as a clinical subentity in squamous cell lung cancer patients | ||
Author: L.S., KOLODZIEJSKI ; S., DYCZEK ; K., DUDA ; J., GORALCZYK ; W.M., WYSOCKI ; W., LOBAZIEWICZ ; | ||
Abstract: Cavity in lung cancer patients is usually attributed to worse prognosis, which
could be caused by diagnostic difficulties and late surgery. The aim of this
study is to identify cavity as clinical subentity in squamous cell lung cancer
(SqCLC) patients. 1094 patients with I0 - III0 of SqCLC underwent surgery with
the purpose of radical lobectomy or pneumonectomy. The patients were divided
into two groups: 100 patients with cavity (cSqCLC) and 994 with solid tumor
(sSqCLC). The clinical, histological and prognostic features were compared for
the both groups. The Cox multivariate analysis of the prognostic factors was
performed. The survival curves for both groups were compared. cSqCLC patients
showed lower body mass and more frequent hemoptoe. They had larger tumors,
located peripherically, rarer nodal involvement and atelectasis. Despite the
similar cancer stage and the exploratory thoracotomies ratio, cSqCLC patients
lived shorter. The survival curves for both groups were different: in all
population, for patients after radical surgery and even after exploratory
thoracotomy. We conclude that the cavitation in SqCLC patients can be regarded
as a separate subentity related to worse prognosis.
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Keywords: Lung cancer, squamous cell, surgery, surival, prognosis, cavitation. | ||
Year: 2003, Volume: 50, Issue: | Page From: 66, Page To: 73 | |
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