Home Bratislava Medical Journal 2012 Bratislava Medical Journal Vol.113, No.6, p.357–360, 2012

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Published Monthly, in English
Founded: 1919
ISSN 0006-9248
(E)ISSN 1336-0345

Impact factor 1.2

 

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Bratislava Medical Journal Vol.113, No.6, p.357–360, 2012

Title: Chlamydial infection in female lower genital tract and its correlation with cervical smear abnormalities
Author: P. Peitsidis, K. Kalmantis, A. Peitsidou, S. Zervoudis, I. Papaspyrou, N. Georgoulias, E. Kioses

Abstract: Background: It is widely known that infection by Chlamydia trachomatis (CT) is the most common curable sexually transmitted infection (STI) among the young population.
Chlamydial cervicitis has been suspected in the past to be a risk factor for squamous intraepithelial neoplasia (SIL) and cervical cancer on the basis of case-control comparisons of serological tests.
Methods: A total of 110 women with symptomatic cervicitis were examined and samples for microbiologic detection of Chlamydia trachomatis antigen were obtained. Colposcopic, cytologic and microbiologic analyses were performed. All results were statistically analysed and correlated.
Results: 41 patients (37.2 %) were found positive for Chlamydia trachomatis antigen (Group I) and 69 patients (62.8 %) were negative for Chlamydia trachomatis antigen (Group II). When compared to group II, the chlamydia-infected group I of women presented a larger percentage of dyspareunia (60 %), and the dysuric complaints were more common. The chlamydia-positive group revealed a higher incidence of atypical squamous metaplasia (52.5 % vs 27.9 %). Among the women with positive ELISA for chlamydia, a higher percentage of low-grade SIL was observed (6.3 % vs 3.6 %).
Conclusions: Chlamydial infection, especially chlamydial cervicitis occurs often among young women of reproductive age. In these women, a good clinical assessment is necessitated including previous clinical history record, as well as detailed microbiologic, cytologic and colposcopic evaluations (Tab. 5, Ref. 19).

Keywords: infection by Chlamydia trachomatis, sexually transmitted infection, cervicitis.
Year: 2012, Volume: 113, Issue: 6 Page From: 357, Page To: 360
doi:10.4149/BLL_2012_081


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