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Bratislava Medical Journal Vol.113, No.8, p.495–497, 2012 |
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Title: Celiac disease and multiple sclerosis in the northwest of Iran | ||
Author: M. Khoshbaten, M. Farhoudi, M. Nikanfar, H. Ayromlou, S. Shaafi, S. A. Sadreddini, A. Pashapoor, A. Taheraghdam, M. Yazdchi, N. Sharifi | ||
Abstract: Objective: To compare the frequency of celiac disease (CD) in patients with multiple sclerosis (MS) and healthy controls using tissue transglutaminase IgA antibodies (anti-tTGA) as a screening tool. Results: The mean age of MS patients (32 male and 68 female) was 33.06±8.79 years; the mean age of controls was 32.98±9.62 years. The mean expanded disability scale score (EDSS) for MS patients was 3.86±1.91. Approximately 78.5 % of MS patients suffered from a remitting relapsing type of MS. All subjects (MS patients and controls) were negative for anti-tTGA. IgA deficiency was demonstrated in 14 % of MS patients and 11 % of controls (p>0.1). No IgA-deficient subjects consented to undergo a duodenal mucosa biopsy.
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Keywords: celiac disease, multiple sclerosis, anti-tissue transglutaminase antibodies. | ||
Year: 2012, Volume: 113, Issue: 8 | Page From: 495, Page To: 497 | |
doi:10.4149/BLL_2012_109 |
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