Home Bratislava Medical Journal 2013 Bratislava Medical Journal Vol.114, No.8, p.460-463, 2013

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Published Monthly, in English
Founded: 1919
ISSN 0006-9248
(E)ISSN 1336-0345

Impact factor 1.2

 

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Bratislava Medical Journal Vol.114, No.8, p.460-463, 2013

Title: Determination of serological profiles and avidity of specific antibodies in the sera of patients with potential Epstein-Barr virus (EBV) infection
Author: N. Akpolat, M. Gedik, S. Nergiz, H. Bilek

Abstract: A total of 522 patient’s sera were sent to The Clinical Microbiology Laboratory for EBV specific antibody detection and were studied by IFA method during a two year period. The serum samples were tested for EBV specific VCA IgG, VCA IgM, EA, EBNA antibodies and VCA IgG aviditity.
Results: Among 33 patients those who had low avidity for VCA IgG, 27 (81.8 %) of them had a serologic profile as follows; positive VCA IgG, negative VCA IgM, negative EA and negative EBNA.
Conclusion: While this profile is considered as a primary infection, the frequency of the coexistence of VCA IgG low avidity with this profile is interepreted that avidity may lead to detect primary infection (Tab. 2, Ref. 25).

Keywords: EBV infection, VCA IgG avidity.
Year: 2013, Volume: 114, Issue: 8 Page From: 460, Page To: 463
doi:10.4149/BLL_2013_096


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