Home Bratislava Medical Journal 2013 Bratislava Medical Journal Vol.114, No.11, p.634-636, 2013

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Published Monthly, in English
Founded: 1919
ISSN 0006-9248
(E)ISSN 1336-0345

Impact factor 1.2

 

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Bratislava Medical Journal Vol.114, No.11, p.634-636, 2013

Title: Flow-mediated vasodilatation in the patients with anorexia nervosa
Author: S. Palova, J. Charvat, J. Chlumsky

Abstract:

Objective: To compare flow-mediated vasodilatation in patients with anorexia nervosa and healthy subjects.
Background: Endothelial dysfunction is present in the patients with anorexia nervosa. However, flow-mediated vasodilatation in the patients with anorexia nervosa in comparison with control subjects has not been yet evaluated.
Methods: Flow-mediated vasodilatation in the brachial artery was examined in 30 patients with anorexia nervosa admitted to metabolic care unit for realimentation and compared to 30 control subjects.

Results: The average age of the patients with mental anorexia was 25.0±5.2 compared to 25.5±4.5 years of the healthy control subjects (NS).

BMI was in 14.0±1.7 kg/m2 in patients with anorexia nervosa comparing to 20.4±1.0 kg/m2 in the healthy control subjects (p<0.001).


The baseline mean diameter of the right brachial artery was 0.33±0.06 cm in the anorexia nervosa patients and 0.35±0.05 cm in the control subjects (NS).

The absolute increase of brachial artery size after reactive hyperemia was 0.029±0.006 cm (9%) in the anorexia nervosa patients and 0.039±0.006 cm (11 %) in the control subjects (p=0.002).

After realimentation, the baseline mean diameter of the right brachial artery was comparable to the result before nutrition intervention – 0.34±0.05 cm but brachial artery increase due to reactive hyperemia was 0.036±0.05 cm (10.5 %).

It was for 19 % higher compared to the first examination (p<0.001).


Conclusion: Flow-mediated vasodilatation is decreased in the patients with anorexia nervosa in comparison with the healthy control subjects and improves after realimentation (Tab. 1, Ref. 20).



Keywords: anorexia nervosa, flow-mediated vasodilatation, realimentation.
Year: 2013, Volume: 114, Issue: 11 Page From: 634, Page To: 636
doi:10.4149/BLL_2013_135


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