Home Bratislava Medical Journal 2014 Bratislava Medical Journal Vol.115, No.10, p.622-624, 2014

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Published Monthly, in English
Founded: 1919
ISSN 0006-9248
(E)ISSN 1336-0345

Impact factor 1.2

 

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Bratislava Medical Journal Vol.115, No.10, p.622-624, 2014

Title: Favourable effect of Eugenol on liver histology in acute cholestasis in rats after bile duct ligation
Author: M. Sarikaya, L. Filik, B. Ergul, Z. Dogan, M. A. Gonultas, S. Hucumenoglu, M. Can, M. E. Duymus

Abstract: Background: Eugenol an essential oil found in clove was previously shown to have some anti-inflammatory properties. It also was shown to be linked to hepatoprotective effect. In this regard, we aimed to reveal the effect of eugenol on cholestatic liver disease.
Method: Cholestatic liver disease model was established in 20 rats via bile duct ligation. Eugenol was administered and cytokine levels and liver histology after sacrifice were evaluated.
Results: Biliary ductular proliferation and neutropil infiltration were lower in eugenol-administered rats.
Conclusion: Eugenol has a promising effect on liver histology in cholestatic liver disease (Tab. 1, Fig. 2, Ref. 16).

Keywords: biliary ductular proliferation, cholestatic liver disease, bile duct ligation, liver histology, acute cholestasis.
Year: 2014, Volume: 115, Issue: 10 Page From: 622, Page To: 624
doi:10.4149/BLL_2014_120


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