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Bratislava Medical Journal Vol.116, No.2, p.124-127, 2015 |
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Title: Appreciation of trimetazidine treatment in experimental sepsis rat model | ||
Author: A. Tanoglu, L. Yamanel, V. Inal, R. Ocal, B. Comert, C. Bilgi | ||
Abstract: Introduction: Our aim was to determine the efficacy of trimetazidine on experimental sepsis rat model. In Group 2, serum GSH-Px and SOD levels were statistically significantly higher than in Group 1 (p< 0.05) and serum MDA levels were statistically significantly lower than in group 1 (p < 0.05). Trimetazidine also significantly decreased the levels of IL-1ß and TNF-a which are the proinflammatory cytokines (p < 0.05).
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Keywords: sepsis, trimetazidine, inflammation, proinflammatory cytokines. | ||
Year: 2015, Volume: 116, Issue: 2 | Page From: 124, Page To: 127 | |
doi:10.4149/BLL_2015_024 |
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