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Endocrine Regulations Vol.49, No.2, p.84-90, 2015 |
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Title: Subclinical hypothyroidism in combination with vitamin D deficiency increases the risk of impaired left ventricular diastolic function | ||
Author: H. Yilmaz, M. Cakmak, T. Darcin, O. Inan, O. M. Gurel, M. A. Bilgic, N. Bavbek, A. Akcay | ||
Abstract: Objective. Subclinical hypothyroidism and vitamin D deficiency are common. The diastolic function of patients with both subclinical hypothyroidism and vitamin D deficiency remains unknown. This study aimed to investigate diastolic dysfunction in patients with both subclinical hypothyroidism and vitamin D deficiency. he patients were divided into 4 groups. Group 1 (n=71) included patients with subclinical hypothyroidism and vitamin D deficiency; Group 2 (n=66) included patients with subclinical hypothyroidism and vitamin D sufficiency; Group 3 (n=65) included euthyroid patients with vitamin D deficiency; and Group 4 (n=52) included euthyroid patients with vitamin D sufficiency. LAVI (31.3±3.2, 28.7±3.0, 28.4±3.4, and 27.9±3.9; p<0.001) and E/E’ values (11.2±2.7, 8.9±2.7, 9.1±2.9, 8.8±2.5; p<0.001) were significantly higher in Group 1 than in Groups 2, 3 and 4. E’ values were significantly lower in Group 1 than in Groups 2, 3 and 4.
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Keywords: vitamin D deficiency, subclinical hypothyroidism, diastolic function, echocardiography | ||
Year: 2015, Volume: 49, Issue: 2 | Page From: 84, Page To: 90 | |
doi:10.4149/endo_2015_02_84 |
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