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Bratislava Medical Journal Vol.116, No.1, p.36-40, 2016 |
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Title: Vitamin C ameliorates high dose Dexmedetomidine induced liver injury | ||
Author: M. Arslan, S. C. Sezen, H. C. Turgut, M. Kocabiyik, H. Arpaci, F. M. Comu, L. Ozturk, M. Kavutcu | ||
Abstract: BACKGROUND: We investigated whether vitamin C has protective effects on rat liver tissue treated with different dexmedetomidine doses. CONCLUSION: High dose dexmedetomidine can induce hepatic injury and oxidative stress in rats while pre-treatment with vitamin C may be effective in protecting liver tissue against this newly recognized undesirable dexmedetomidine effect (Tab. 2, Fig. 5, Ref. 30). |
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Keywords: Dexmedetomidine, vitamin C, liver histopathology, MDA, SOD, rat | ||
Published online: 21-Jan-2016 | ||
Year: 2016, Volume: 116, Issue: 1 | Page From: 36, Page To: 40 | |
doi:10.4149/BLL_2016_008 |
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