Bratislava Medical Journal Vol.118, No.1, p.51-55, 2017

Published Monthly, in English
Founded: 1919
ISSN 0006-9248
(E)ISSN 1336-0345

Impact factor 1.564

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Bratislava Medical Journal Vol.118, No.1, p.51-55, 2017
Title: Assessing the level of matrix metal proteinases 1,8,9, their tissue inhibitor, type I, in cases of odontogenic phlegmons
Author: E. V. Markelova, A. L. Romanchuk, E. V. Prosekova, V. E. Krasnikov, S. N. Beniova

Abstract: The article considers the measured values of the level of MMP-1, MMP-8 and MMP-9, and of their tissue inhibitor Type I (TIMP-1) in the blood serum and mixed saliva samples of 78 patients (31 women – 36.2 %, 47 men – 63.8 %) suffering from odontogenic phlegmons in the oral and maxillofacial region. The study indicators were assessed through the enzyme-linked immunosorbent assay using diagnostic sets RandD Diagnostics Inc. (USA). An uncontrolled hyperactivation of metal proteinases as one of the components of the systemic inflammatory response in case of phlegmon-related complications in the oral and maxillofacial region, as well as development of the sepsis syndrome were studied and it was determined that it results in distortion of the processes of reparative hystogeny and compel us to employ new approaches to the treatment of this type of patients (Tab. 2, Fig. 1, Ref. 13).

Keywords: metal proteinases, tissue inhibitor of metal proteinases, odontogenic phlegmons.
	Published online: 26-Jan-2017
Year: 2017, Volume: 118, Issue: 1	Page From: 51, Page To: 55
doi:10.4149/BLL_2017_010
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